Fort Dodge Fire Department responded to the fire at 629 Central Avenue shortly 2:00 p.m.
When they arrived smoke was coming from an apartment.
A resident of the building had called 911 after smelling smoke and activated the smoke alarm.
Fire fighters discovered an adult female unresponsive in the apartment.
She died of her injuries with the body taken to the State Medical Examiner’s Office in Ankeny.
The name of the victim has not been released.